What do T-helper cells primarily assist in?

T-helper cells play a crucial role in the immune response, primarily by activating and directing other immune cells. They are essential for the activation of B cells and cytotoxic T cells. When T-helper cells encounter antigens presented on major histocompatibility complex (MHC) molecules by antigen-presenting cells, they become activated and secrete cytokines. These cytokines then stimulate B cells to produce antibodies, enhancing the humoral immune response, and also activate cytotoxic T cells, which are vital for the cell-mediated immune response.

This interaction is fundamental to the adaptive immune system, allowing it to tailor a robust defense against specific pathogens. By facilitating the activation of other lymphocytes, T-helper cells ensure that the immune system can effectively respond to infections and develop immunological memory, leading to quicker responses to future infections by the same pathogen.